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The Progress Report Progress never stops. Stay informed with the latest news on breast cancer research, treatment, and prevention.



portrait of mackenzie smiling and looking at the camera

A month into dating, Mackenzie Dougherty, 35, decided to tell her new boyfriend, David, that she carried the BRCA1 gene mutation.

“But I didn’t expect we would have to fight breast cancer together anytime soon,” she said.

Screenshot of a title slide introducing the video with Dr. Levy-Lahad's headshot

We know that when a woman finds out she has an inherited gene mutation, such as BRCA1 or 2, she can significantly reduce her risk of breast cancer if she undergoes a preventative mastectomy.

Video title slide that says Watch the Video: What Men Should Know about BRCA Genes

Many of us are familiar with the BRCA1 and BRCA2 genes that, when mutated, are linked to an increased risk of breast cancer in women. But less often discussed is how BRCA gene mutations (and other, less-commonly known gene mutations) can affect men.

Identifying high-risk individuals is key to preventing breast cancer

Mutations, or alterations, in the “cancer-fighting” genes BRCA1 or BRCA2, can dramatically increase person’s risk of breast cancer. Women with a mutation in BRCA1/2 have a 6-7 times greater risk of developing breast cancer and men with the mutation have an over 80 times greater risk.

The discovery of the BRCA1 and BRCA2 genes more than 20 years ago dramatically changed risk assessment, prevention and treatment in families with a high prevalence of breast and/or ovarian cancers.

BCRF grantee Dr. Susan Domchek spoke to us about a  new study she co-authored on genetic testing for breast cancer in the “New England Journal of Medicine.” Dr. Domchek explains:

You asked, we listened and the answers are in.

Our #AskBCRF social media event was tailored for those who have been diagnosed with breast cancer – their siblings, children and relatives – who had questions surrounding inherited susceptibility to breast and ovarian cancer.

After actress and filmmaker Angelina Jolie Pitt revealed she underwent two preventive surgeries to remove her ovaries, fallopian tubes, and both breasts because she carries a B

On Tuesday, March 24, actress Angelina Jolie Pitt penned an op-ed in The New York Times revealing she had preventative surgery to remove her fallopian tubes and ov