You are here

The Progress Report Progress never stops. Stay informed with the latest news on breast cancer research, treatment, and prevention.

Tag:

Genetics x

Genetic testing for mutations in the BRCA1 and BRCA2 genes has dramatically improved our ability to understand risk of cancer in families with a high incidence of breast and ovarian cancers.

Tags:

In a recent report from the New York Breast Cancer Study, led by BCRF investigator Mary Claire King, testing for breast cancer risk using a multigene panel was carried out for 1,007 Ashkenazi Jewish women with breast cancer.

Tags:

Our ability to probe deeply in the genome of normal and cancer cells continues to inform our understanding of the causes of breast cancer.

Tags:

Studies released today in Nature and Nature Genetics, supported in part by BCRF, reported findings by a major international consortium identifying 72 previously unknown common genetic variants that predispose individuals to breast cancer and seven others that are specific for tr

Tags:

The discovery of the BRCA1 and BRCA2 genes more than 20 years ago dramatically changed risk assessment, prevention and treatment in families with a high prevalence of breast and/or ovarian cancers.

In January of this year, the American Association for Cancer Research (AACR) released a special report outlining its view on how cancer prevention will change in the era of precision medicine and immune-oncology.

PARP inhibitors are drugs that target tumors with BRCA1/BRCA2 mutated cells and the first PARP inhibitor was approved in 2015 as a targeted therapy for ovarian cancer patients with BRCA1/2 mutations.

A paper authored by BCRF investigator Dr. Kerstin Meyer of University of Cambridge, has identified 36 overlapping collections of genes (known as “regulons”) that are associated with increased breast cancer risk.

Tags:

A new BCRF-funded study published in the Journal of the National Cancer Institute provides new insight on an aggressive form of breast cancer frequently diagnosed in African-American women.

BCRF grantee Dr. Susan Domchek spoke to us about a  new study she co-authored on genetic testing for breast cancer in the “New England Journal of Medicine.” Dr. Domchek explains: