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The Progress Report Progress never stops. Stay informed with the latest news on breast cancer research, treatment, and prevention.


HER2 x

portrait of uma iyengar

About two years ago, Uma and her husband, Mukund, temporarily relocated from Chicago to New York City to be close to “the babies,” as she affectionately calls her grandchildren. Her son Dr.

Since 1989, breast cancer deaths have declined by 40 percent—a statistic that can be attributed in large part to advances in treatment.

chemotherapy IV against blue background

Treatment optimization–balancing efficacy with toxicity–remains a clinical challenge in early-stage breast cancer and was a major focus of clinical trials featured at this year’s virtual annual meeting of the American Society of Clinical Oncology (ASCO). Below are key highlights:


HER2-positive breast cancer represents about 25 percent of all breast cancers. Once a deadly disease with few treatment options, early stage HER2-positive breast cancer is now a treatable disease with a good prognosis for many patients.

Metastasis, when cancer cells leave the breast and spread to other sites in the body, is the major cause of mortality from breast cancer. Common sites of breast cancer metastasis are bone, lung, liver and brain.

Dr. Loi received her first BCRF research grant in 2014, but was no stranger to the BCRF researcher community.

The last full day of SABCS 2015 started with a discussion on the past and future directions of HER2- directed therapies. In his lecture, Dr.

A team of Yale researchers has discovered a new complexity in drug resistance that may lead to the development of future therapies for patients with HER2-positive breast cancer.