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The Progress Report Progress never stops. Stay informed with the latest news on breast cancer research, treatment, and prevention.

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Metastatic breast cancer (MBC), also referred to as stage IV or advanced breast cancer, is incurable and responsible for virtually all breast cancer related deaths, leading to more than 40,000 deaths in women and men in the U.S. each year.

Metastasis – the process where cancer spreads to other tissues – is a complex, multi-step process. Most cancer cells do not survive the journey. Those that do, and form new tumors at a different site, are the leading cause of breast cancer deaths.

Tumors are not made up of a homogenous group of cancer cells. In fact, they are made up of a variety of cancer cells. Researchers are determined to understand these cell types and how they contribute to breast cancer growth.

Metastasis occurs when a cancer cell leaves the tissue from which it originated and forms a new tumor in a different organ. When breast cancer spreads to the brain, known as brain metastasis, few treatment options exist.

Each year, BCRF convenes its researchers from around the world for an exclusive research retreat in New York City. The research retreat has been part of BCRF’s annual October events since the early 2000’s spurred by Scientific Director, Dr.

Editor's Note: It is with great sadness that we share the news that Larissa Podermanski passed away from metastatic breast cancer on May 10, 2018. Larissa was a passionate advocate for research and used her personal blog Metastatically Speaking to candidly share her desire to live with purpos

Hormone Receptor Positive Breast Cancer: CDK4/6 inhibitors 

BCRF previously reported on updates of a new class of drugs called CDK4/6 inhibitors in clinical trials for hormone receptor positi