Most women diagnosed with breast cancer will undergo some type of surgery as part of their treatment plan. One of the main options is a mastectomy, a procedure that surgeons have been performing for hundreds of years to remove one or both breasts. Choosing to have a mastectomy isn’t easy, of course: You and your doctor will need to discuss many factors to help you decide if a mastectomy is the right option for your situation.
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Read on to learn when the procedure is and isn’t recommended, the various types of mastectomies performed, and what you can expect during the recovery process.
The term mastectomy comes from the Greek word for breast: “mastos.” It’s a surgical procedure to remove all the tissue from one or both breasts. The operation traditionally included removal of the nipple, areola, and breast skin, but you may be a candidate for newer types of mastectomies that allow you to keep them.
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A mastectomy may also involve more than removal of the breast and may be combined with other procedures. For example, if your cancer has spread from the breast to the lymph nodes under your arm, your surgeon may remove them during your mastectomy. In rare cases, the pectoral (chest wall) muscles are also excised in what’s called a radical mastectomy, detailed below. And if you opt for breast reconstruction, your surgeon can perform the procedure at the same time as your mastectomy.
A mastectomy is performed as a treatment for breast cancer since the procedure is a physical removal of cancer cells and tumors from breast tissue; this can also help prevent breast cancer from spreading (metastasizing) to other sites in the body. This is particularly important since once the cancer has spread from the breasts and nearby lymph nodes—a.k.a. stage 4 or metastatic breast cancer—it may be treated but it is no longer curable. Mastectomy may also be recommended to prevent breast cancer in women who are at high risk of developing the disease.
What stage of breast cancer requires a mastectomy? It’s an option for nearly every stage and type of the disease, including:
Disease stage isn’t the only factor doctors consider when recommending a mastectomy versus a lumpectomy, the other main type of breast cancer surgery in which only a portion of the breast tissue is removed. Lumpectomies are considered breast-conserving surgery since a small lump is generally removed, preserving most of the breast tissue. A lumpectomy or mastectomy is almost always followed by radiation and so avoiding them may be preferable if you’re pregnant and don’t want to expose the fetus to radiation or if you’ve previously been treated with radiation and the cancer has recurred.
Your doctor may also recommend a mastectomy if:
Mastectomies are not recommended for some women, such as those with metastatic breast cancer, since it has already spread beyond the breast. Your doctor may also advise against a mastectomy if you’re older, have other major medical conditions, are at a high risk of dying from surgery or anesthesia, or if the procedure is extremely difficult to perform due to the size of the cancer.
A unilateral mastectomy refers to the removal of tissue from one breast. Your surgeon may recommend this procedure if your cancer is only in one breast and you don’t have a high risk of cancer occurring in both breasts.
During a bilateral mastectomy—also called a double mastectomy—the surgeon removes both of your breasts. Most breast cancer patients won’t need a double mastectomy, but it may be necessary in certain circumstances, including if you have cancer in both breasts and/or you have previously received radiation to your chest.
Genetics and family history are also a consideration when choosing between bilateral mastectomy or unilateral mastectomy. You may benefit from a prophylactic/preventive bilateral mastectomy if you have genetic mutations that increase your risk of breast cancer (BRCA1, BCRA2, etc.) and/or you have several close family members who have been diagnosed with breast cancer at a young age. (See “What’s a prophylactic mastectomy?” below.)
Some women with cancer in one breast opt for a double mastectomy to make their breasts more symmetrical. Others may remove both breasts out of concern the cancer will occur in the other breast. But unless you’re at high risk of developing cancer in the healthy breast, there’s no overall survival benefit in removing both breasts.
There are four main types of mastectomies, and the best approach for you is determined by factors such as your age, overall health, tumor size and stage, lymph node involvement, and more. Options include the following:
Simple (or total) mastectomy: This is the most common type of mastectomy. The surgeon removes the breast tissue and possibly the breast skin, nipple, and areola as well. A total mastectomy is most likely to be recommended if the cancer has not spread beyond your breast or you’re removing your breasts to lower your risk of developing breast cancer.
Skin-sparing mastectomy: This type of mastectomy is a modified version of a simple mastectomy that preserves as much of the breast skin as possible. Most women are candidates for this procedure, but it’s not recommended for those who aren’t getting immediate breast reconstruction because the remaining skin may fold and contract. It may also be unadvisable if your tumors are large or close to the surface of the skin.
Nipple-sparing mastectomy: If there is no cancer in your nipple or the tissue just beneath it, you may be able to have a nipple-sparing mastectomy. However, it is only recommended if you’re undergoing immediate breast reconstruction.
Modified radical mastectomy: This procedure is usually performed in women whose breast cancer has spread to the lymph nodes, as both breast tissue and lymph nodes are removed during a modified radical mastectomy.
Rarely, a woman may need to undergo a radical mastectomy, meaning the entire breast, axillary (underarm) lymph nodes, and the pectoral (chest wall) muscles are removed.
The procedure, first performed in 1882, was the standard of care for treating breast cancer for close to a century. While effective, the procedure was aggressive and highly disfiguring, and it was virtually abandoned by the 1970s.
Thanks to major advances in our understanding of breast cancer biology, chemotherapy, radiation therapy, etc., more conservative procedures like simple mastectomies and lumpectomies with radiation have largely replaced radical mastectomies. The only reason they may be recommended now is if breast tumor is growing into the chest muscles.
While mastectomies are most often performed to treat breast cancer, some women at high risk of breast cancer choose to have a prophylactic mastectomy, also called a preventive mastectomy, to lower their chance of developing the disease.
If genetic testing reveals that you carry a genetic mutation associated with a high risk of breast cancer (BRCA1, BCRA2, TP53, PTEN), undergoing a prophylactic mastectomy can decrease your risk dramatically. Research shows that a bilateral prophylactic mastectomy reduces the risk of breast cancer by 95 percent in patients with a BRCA1 or BRCA2 mutation, and by 90 percent in those with a strong family history of breast cancer.
Other reasons you may choose to undergo a prophylactic mastectomy include:
It typically takes three to four weeks to recover from a mastectomy, regardless of the type of mastectomy you have. Mastectomy recovery mostly occurs at home, since many patients can go home the same day of their surgery or the following day. However, you may need to stay in the hospital for up to four or five days if you had a mastectomy with immediate autologous reconstruction (breast reconstruction using your own tissue).
When you wake after surgery, you may not feel much pain because the surgeon has injected a lot of numbing medication into your tissues. If you had immediate breast reconstruction, you may notice tightness and pressure in your chest. As the numbing medication wears off, your doctor may prescribe painkillers, though many women can get relief from over-the-counter pain medication such as ibuprofen and acetaminophen.
When you’re ready to leave the hospital, your doctor will provide you with a list of instructions for home recovery. It includes information about:
Surgery for breast cancer. (n.d.). Breast Cancer Treatment | American Cancer Society. https://www.cancer.org/cancer/types/breast-cancer/treatment/surgery-for-breast-cancer.html
Freeman, M. D., Gopman, J. M., & Salzberg, C. A. (2018). The evolution of mastectomy surgical technique: from mutilation to medicine. Gland Surgery, 7(3), 308–315. https://doi.org/10.21037/gs.2017.09.07
Mastectomy – Mayo Clinic. (n.d.). https://www.mayoclinic.org/tests-procedures/mastectomy/about/pac-20394670
Articles. (n.d.). https://www.cedars-sinai.org/health-library/tests-and-procedures/m/mastectomy.html
Professional, C. C. M. (2025c, March 19). Mastectomy. Cleveland Clinic. https://my.clevelandclinic.org/health/procedures/21221-mastectomy
Breast cancer stages – Moffitt Cancer Center (n.d.). https://www.moffitt.org/cancers/breast-cancer/diagnosis/stages/
Lumpectomy – Mayo Clinic. (n.d.-b). https://www.mayoclinic.org/tests-procedures/lumpectomy/about/pac-20394650
Adams, M. (2022, December 9). What is a double mastectomy? MD Anderson Cancer Center. https://www.mdanderson.org/cancerwise/what-is-a-double-mastectomy.h00-159545268.html
Professional, C. C. M. (2025d, March 19). Prophylactic (Preventative) mastectomy. Cleveland Clinic. https://my.clevelandclinic.org/health/treatments/24025-prophylactic-mastectomy
Surgery to reduce the risk of breast Cancer fact sheet. (2025, January 31). Cancer.gov. https://www.cancer.gov/types/breast/risk-reducing-surgery-fact-sheet
Keelan, S., Flanagan, M., & Hill, A. D. K. (2021). Evolving Trends in Surgical Management of Breast Cancer: An analysis of 30 years of practice changing papers. Frontiers in Oncology, 11. https://doi.org/10.3389/fonc.2021.622621
Mastectomy. (n.d.). https://www.cancer.org/cancer/types/breast-cancer/treatment/surgery-for-breast-cancer/mastectomy.html
Cotlar, A. M., Dubose, J. J., & Rose, D. (2003). History of surgery for breast cancer: radical to the sublime. Current Surgery, 60(3), 329–337. https://doi.org/10.1016/s0149-7944(02)00777-8
Goethals, A., Menon, G., & Rose, J. (2024b, November 10). Mastectomy. StatPearls – NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK538212/
Hammer, C., Fanning, A., & Crowe, J. (2008). Overview of breast cancer staging and surgical treatment options. In Cleveland Clinic, CLEVELAND CLINIC JOURNAL OF MEDICINE (Vol. 75, Issue SUPPLEMENT 1, p. S10). https://www.ccjm.org/content/ccjom/75/3_suppl_1/S10.full.pdf
Fn, J. W. R. M. (2023, February 1). Mastectomy: Overview. Verywell Health. https://www.verywellhealth.com/types-of-mastectomy-breast-surgery-3157281
Tan, S. (2024, February 23). What to know about skin sparing mastectomies. WebMD. https://www.webmd.com/breast-cancer/what-to-know-about-skin-sparing-mastectomies
Articles. (n.d.-b). https://www.cedars-sinai.org/health-library/diseases-and-conditions/n/nipple-sparing-mastectomy.html
Anthony, K. (2021, April 28). What is modified radical mastectomy (MRM)? Healthline. https://www.healthline.com/health/modified-radical-mastectomy#vs-radical-mastectomy
Lymph node surgery for breast cancer. (n.d.-b). American Cancer Society. https://www.cancer.org/cancer/types/breast-cancer/treatment/surgery-for-breast-cancer/lymph-node-surgery-for-breast-cancer.html
Refinetti, A. P. C., MD. (2024b, November 13). Mastectomy recovery: What to expect after breast removal surgery. MD Anderson Cancer Center. https://www.mdanderson.org/cancerwise/mastectomy-recovery–what-to-expect-after-breast-removal-surgery.h00-159702279.html
Mph, C. M. R. (2022, November 17). How to recover after a mastectomy. Verywell Health. https://www.verywellhealth.com/post-mastectomy-care-6823753
Ms, J. C. (2024, January 2). Surgical drains after breast surgery. Verywell Health. https://www.verywellhealth.com/managing-your-surgical-drains-following-breast-surgery-4021630
Exercising after breast cancer surgery. (n.d.). American Cancer Society. https://www.cancer.org/cancer/types/breast-cancer/treatment/surgery-for-breast-cancer/exercises-after-breast-cancer-surgery.html
Before and after mastectomy. (n.d.) USCF Helen Diller Comprehensive Cancer Center https://cancer.ucsf.edu/breastcarecenter/treatment/surgical_oncology/recommendations_mastectomy
Mastectomy (Breast removal surgery). (2023, September 27). WebMD. https://www.webmd.com/breast-cancer/mastectomy
Information and articles in BCRF’s “About Breast Cancer” resources section are for educational purposes only and are not intended as medical advice. Content in this section should never replace conversations with your medical team about your personal risk, diagnosis, treatment, and prognosis. Always speak to your doctor about your individual situation.
BCRF’s “About Breast Cancer” resources and articles are developed and produced by a team of experts. Chief Scientific Officer Dorraya El-Ashry, PhD provides scientific and medical review. Scientific Program Managers Priya Malhotra, PhD, Marisa Rubio, PhD, and Diana Schlamadinger, PhD research and write content with some additional support. Director of Content Elizabeth Sile serves as editor.
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