Palbociclib (Ibrance®)

Palbociclib (Ibrance) is a drug is used in combination with aromatase inhibitors such as fulvestrant in postmenopausal breast cancer patients who were not previously treated with hormone therapy. Palbociclib is part of a group of drugs called CDK4/6 inhibitors. It works by interrupting signals that stimulate the division and growth of cancer cells. The drug is commonly used to treat hormone receptor–positive and HER2-negative breast cancer that has spread to neighboring or distant tissues. Palbociclib is administered orally.