Sacituzumab govitecan-hziy (Trodelvy®)

This antibody-drug conjugate consists of a monoclonal antibody linked to a toxic drug called SN-38. It works by attaching to TROP2 protein found on cancer cells thereby stopping them from growing. It’s given to patients with metastatic hormone receptor–positive/HER-negative breast cancer and metastatic triple-negative breast cancers that have not responded to previous treatments. It’s administered through an IV.